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Big Endothelin-1 is precursor of endothelin 1. Big endothelin-1 is cleaved to yield endothelin-1 via the activity of an endothelin-converting enzyme (ECE). Big Endothelin-1 can be hydrolyzed by chymase to generate endothelin 1 (1-21) in vitro. Endothelins are endothelium-derived vasoconstrictor peptides.
ARCND3; Big endothelin-1; EDN1; endothelin 1; endothelin-1; Et1; ET-1; HDLCQ7; PPET1; preproendothelin; preproendothelin-1; preproET; QME
100 µL
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